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Genisphere 特約代理

描述:Genisphere代理,Genisphere中國代理,Genisphere上海代理,Genisphere總代,Genisphere
Genisphere專業(yè)代理-上海起發(fā)實驗試劑有限公司,具體產(chǎn)品信息歡迎電詢:4006551678

更新時間:2015-12-17
訪問次數(shù):1319
廠商性質(zhì):代理商
詳情介紹

世界*實驗材料供應(yīng)商Genisphere  正式授權(quán)上海起發(fā)為其中國代理,Genisphere  在一直是行業(yè)的*,一直為廣大科研客戶提供zui為優(yōu)質(zhì)的產(chǎn)品和服務(wù),上海起發(fā)一直秉承為中國科研客戶帶來的產(chǎn)品,的服務(wù),簽約Genisphere  就是為了給廣大科研客戶帶來更加完善的產(chǎn)品和服務(wù),您的滿意將是我們zui大的收獲

Genisphere  中國代理,Genisphere  上海代理,Genisphere  北京代理,Genisphere  廣東代理,Genisphere  江蘇代理Genisphere  湖北代理,Genisphere  天津,Genisphere  黑龍江代理,Genisphere  內(nèi)蒙古代理,Genisphere  吉林代理,Genisphere  福建代理,Genisphere  江蘇代理,Genisphere  浙江代理,Genisphere  四川代理,

 

Genisphere公司專注于核酸標(biāo)記技術(shù)的發(fā)明和新產(chǎn)品的開發(fā)。該公司推出的3DNA Dendrimer技術(shù)是對核酸標(biāo)記技術(shù)的重大創(chuàng)新,具有廣闊的發(fā)展前景。3DNA Dendrimer技術(shù):3DNA Dendrimer是由多個交錯的自然或合成的3DNA單體結(jié)構(gòu)單位組成的復(fù)雜的分枝狀分子構(gòu)型。每個3DNA單體由兩條中央部分互補的DNA鏈組成,退火時兩條鏈會形成一個中間雙鏈兩頭單鏈的結(jié)構(gòu)。3DNA單體之間的單鏈通過堿基互補組成了3DNA Dendrimer構(gòu)型。3DNA Dendrimer的單鏈?zhǔn)菢?biāo)記物的結(jié)合位點。特點:靈活的標(biāo)記:3DNA Dendrimer可以結(jié)合多種標(biāo)記物,可以滿足多種檢測的需要
信號增強作用:每個3DNA Dendrimer分子平均可以結(jié)合200分子的標(biāo)記物,因此雜交時信號增強了200倍以上

In 1986, the first patent applications covering the design and use of 3DNA technologywere filed. Determined to build a strong portfolio and reward our scientists, we have worked hard to grow the list of patents. Genisphere was incorporated in 1997 and proudly launched its first 3DNA Expression Array Detection kit, developed in conjunction with Harvard-affiliated researchers, in 1999.

In 2006, Genisphere was honored to receive a Frost & Sullivan Technology Innovation Award for this product line. With an established business in microarrays, Genisphere turned to RNA amplification technology, offering a new method with a twist—the ability to amplify mRNA in the sense orientation. Product launches included SenseAMP in 2004, RampUP in 2006, and Sensation in 2011. All had a particular focus on clinical FFPE samples. In 2008, Genisphere’s RNA amplification technology was incorporated into the Pathwork Diagnostics Tissue of Origin Test, which was cleared by the FDA in 2010. The Sensation technology was licensed to Affymetrix in 2011 for microarray applications. Genisphere launched the world’s first microRNA labeling kit in 2005. The release of FlashTag in 2007 enabled customers to scale up their microRNA research, offering a single-tube labeling reaction with no purification required. Genisphere’s microRNA labeling technology has been incorporated into microarray products from Invitrogen (2006, 2008) and Luminex products from Marligen (2008). Additional co-marketing (2009) and OEM (2011) structures with Affymetrix validate the power of FlashTag. Single-tube UltraAmp reagents were first launched in 2005, with new varieties added in 2008. Now almost all UltraAmp signal amplifiers are custom made, once again proving the importance of collaboration. Genisphere found particular success in providing custom reagents to improve the limit of detection in lateral flow point-of-care diagnostic tests and licensed 3DNA technology to BBI Solutions for lateral flow assay development for enhanced performance and sensitivity (2014).

In 2009, Genisphere LLC was formed, inheriting all of the legacy technology and inlectual property from its predecessor, Genisphere, Inc. With established success of the 3DNA technology in life science and diagnostic applications, the company turned its focus to targeted drug delivery. Since research has shown DNA to be a non-toxic, biocompatible material in vivo, Genisphere aimed to become a commercial source of highly targeted DNA-based nanocarriers. Genisphere's first task was to re-engineer its DNA strands based on three goals for the final 3DNA construct.

  1. Redesigning the DNA sequences with the immune system in mind
  2. Incorporating more crosslinking sites for better stability of the core 3DNA structure
  3. Scaling up the manufacturing process to achieve routine production of therapeutic quantities of 3DNA

After meeting these objectives, Genisphere expanded its efforts in cellular targeting. Leveraging its experience in antibody-DNA conjugation, the company studied attachment of 3DNA to antibody fragments, peptides, sugars, vitamins and other targeting devices for specific cellular delivery. After producing these data, Genisphere established several key collaborations to generate preclinical data showing the versatility and efficacy of the 3DNA platform in targeted delivery of small drugs, biologics and nucleic acids. To date, the 3DNA platform has proven to provide cell-specific (cytosolic and nuclear) delivery of drugs with functional intracellular effects without apparent toxicity. The flexibility of the 3DNA platform to deliver hundreds of tracking labels to targeted tissues provides an option to incorporate a companion diagnostic into the drug development process. Genisphere continues to seek partnerships with biotechnology and pharmaceutical companies. The company is also advancing its own lead oncology compounds based on the 3DNA drug delivery platform.


公司:www.genisphere.com/

 

我們公司zui大優(yōu)勢是強大的采購,

1:基本什么都能進口,血清,抗體,耗材,還有部分限制進口的,

2:貨品全,現(xiàn)經(jīng)營過700多個品牌,基本所有生物試劑耗材都可以進口,特別是冷偏的產(chǎn)品那就更有優(yōu)勢,

3:提供加急服務(wù),一般1-2周到貨,超過時限加急費全免

4:價格公道,絕大部分價格有優(yōu)勢,當(dāng)然不能保證100%產(chǎn)品都是,因為意味著沒有服務(wù).

5:良好的信譽,大部分客戶我們提供貨到付款服務(wù),客戶包括清華,北大 交大 復(fù)旦,中山等100多所大學(xué),ROCHE,阿斯利康,國藥 ,fisher等500多家公司

6:我們還是Santa,Advanced Biotechnologies Inc,Genisphere ,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, GePromegaridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,Genisphere , Polysciences,prospecbi, QA-BIO,quickzyme,FULLERLABS,INC,sterlitech;sysy,TriLink BioTechnologies,Inc;worthington-biochem,zyagen等幾十家國外公司授權(quán)代理。
7:我們還是invitrogen,qiagen,Genisphere am,sigma;Promega,roche,merck, rnd,BD, GE,pierce,BioLegend等*批發(fā),歡迎合作。

 

上海起發(fā)實驗試劑有限公司
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